EAS Lipid Registry of Africa (EAS-LIPRA)
Synopsis – EAS-LIPRA brought together investigators from multiple African countries with support from various regions of the Western world with an interest in dyslipidaemia, preventive cardiology and patient care. This registry is envisaged to expand its reach across Africa and broadly facilitate multiple lines of scientific inquiry in lipidology and preventive cardiology through multisite participation. The outputs of this work are expected to inform and help improve clinical practice in that underrepresented part of the world.
Publications
Lyons ARM, Raal FJ, Mansfield BS et al. Proposed lipidology and preventive cardiology research priorities in Africa; Results of a Delphi survey. ATHEROSCLEROSIS PLUS 2025; 61:18-22. doi.org/10.1016/j.athplu.2025.05.003
Video presentation of above article
Reda A, Lyons ARM, Zambon A et al. A collaborative effort across Africa to investigate risk factors and outcomes of premature acute coronary syndrome: Protocol for the EAS Lipid Registry of Africa (LIPRA). ATHEROSCLEROSIS PLUS 2024; 58:46-50. doi.org/10.1016/j.athplu.2024.10.002
EAS-LIPRA Newsletter (Editor)
Issue 1, January 2025
Issue 2, June 2025
Issue 3, January 2026
Issue 4, March 2026
International Committee Meetings
Lyons ARM, on behalf of EAS-LIPRA. Executive & Steering Committees Briefing: ‘EAS-LIPRA Project Overview and Direction’. EAS-LIPRA Closed Meeting at the EAS 93rd Congress, Glasgow, UK; 04-05-2025.
Lyons ARM, on behalf of EAS-LIPRA. Executive & Steering Committees Briefing: ‘EAS-LIPRA Project Status 2024’. EAS-LIPRA Closed Meeting at the EAS 92nd Congress, Lyon, France; 26-05-2024.
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EAS Lipid Clinic Network (EAS-LCN)
Synopsis – EAS-LCN is a collaboration with established lipid clinics, globally, to address the challenges in the management of dyslipidaemias through harmonisation of efforts via shared experiences and knowledge exchange to assess, inform, improve and disseminate standardised guidelines of practice.
Educational Programmes
Industry-sponsored, EAS lipidology on-demand course with an application in progress for CME accreditation (coordination). Course live online.
Industry-sponsored, EAS lipidology workshops (coordination) in UK, Italy & Germany.
International webinar series on the published 2025 updated ESC/EAS dyslipidaemia guidelines (coordination) for Brazil, Georgia, Iraq, Norway, Uzbekistan, Bosnia & Herzegovina, Luxembourg, Greece, Colombia, Kazakhstan, Pakistan, Japan, Argentina, Egypt, Spain, Portugal, Denmark, Lithuania, Russia.
International webinar series on the published EAS systemic metabolic disease management consensus (coordination) for Brazil, Czech Republic, Estonia, Greece, Georgia, Iraq, Kazakhstan, Lithuania, Pakistan, Portugal, Romania, Russia, Uzbekistan.
Publications
Lipid clinic position paper (writing group coordination).
Survey Research
Industry-sponsored, cardiovascular and lipidology related surveys (x3) on the EAS-LCN (coordination).
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Industry-Sponsored Public Health Research
Written Report to Sponsor
Global distribution of cardiovascular disease risk factors in an international cohort that attended the EAS health check booth from 5th – 7th May 2025.
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Independent Portfolios of Consultants
Dr. Alexander R.M. Lyons, Ph.D
Personal Publication Track-Record of Projects from Career History
Lyons ARM, Raal FJ, Mansfield BS et al. Proposed lipidology and preventive cardiology research priorities in Africa; Results of a Delphi survey. ATHEROSCLEROSIS PLUS 2025; 61:18-22. doi.org/10.1016/j.athplu.2025.05.003
Elshorbagy A, Vallejo-Vaz AJ, Barkas F et al. Global prevalence of overweight and obesity among children and adults with heterozygous familial hypercholesterolemia, and their associations with cardiovascular disease. EUROPEAN HEART JOURNAL 2025; ehae791. doi.org/10.1093/eurheartj/ehae791
Reda A, Lyons ARM, Zambon A et al. A collaborative effort across Africa to investigate risk factors and outcomes of premature acute coronary syndrome: Protocol for the EAS Lipid Registry of Africa (LIPRA). ATHEROSCLEROSIS PLUS 2024; 58:46-50. doi.org/10.1016/j.athplu.2024.10.002
[*Equal contributions] Elshorbagy A*, Lyons ARM*, Vallejo-Vaz AJ et al. Association of BMI, lipid-lowering medication, and age with prevalence of diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study by the EAS FHSC. THE LANCET DIABETES & ENDOCRINOLOGY 2024; 12(11):811-823. doi.org/10.1016/S2213-8587(24)00221-3
Mulder JWCM, Tromp TR, Al-Khnifsawi M et al. Sex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia. JAMA CARDIOLOGY 2024; 9(4):313-322. doi.org/10.1001/jamacardio.2023.5597
Lyons ARM, Stevens CAT, Dharmayat KI et al. Overview of a collaborative global effort to address the burden of familial hypercholesterolaemia. INDIAN HEART JOURNAL 2024; 76:S113-116. doi.org/10.1016/j.ihj.2023.11.005
Dharmayat KI, Vallejo-Vaz AJ, Stevens CAT et al. Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study. THE LANCET 2024; 403(10421):55-66. doi.org/10.1016/S0140-6736(23)01842-1
Stevens CAT, Lyons ARM, Dharmayat KI et al. Ensemble Machine Learning Methods in Screening Electronic Health Records: A Scoping Review. DIGITAL HEALTH 2023; May 9;9:20552076231173225. doi.org/10.1177/20552076231173225
Stevens CAT, Lyons ARM, Dharmayat KI et al. FindMyLipidClinic.com: A global directory of lipid clinics and patient organisations to improve dyslipidaemia care. EUROPEAN ATHEROSCLEROSIS JOURNAL 2022; 2:37-40. doi.org/10.56095/eaj.v1i2.11
Tromp TR, Hartgers ML, Hovingh GK et al. Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study. THE LANCET 2022; 399(10326):719-728. doi.org/10.1016/S0140-6736(21)02001-8
Vallejo-Vaz AJ, Stevens CAT, Lyons ARM et al. A global perspective on familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). THE LANCET 2021; 398(10312):1663-1776. doi.org/10.1016/S0140-6736(21)01122-3
Lyons, ARM. The Effect of Isokinetic Exercise on Biofluid Matrices as Measured by 1H NMR Spectroscopy. Ph.D THESIS, University of East London, London UK. 2016.